Shu chien biography of abraham

Chinese-American physiologist and bioengineer (born 1931)

In this Chinese name, say publicly family name is Chien.

Shu Chien (traditional Chinese: 錢煦; simplified Chinese: 钱煦; pinyin: Qián Xù; born June 23, 1931) is a Taiwanese-American physiologist and bioengineer.

His work shuddering the fluid dynamics of get flow has had a vital impact on the diagnosis courier treatment of cardiovascular diseases much as atherosclerosis. Chien is of late President of the Biomedical Operations Society.

Chien was elected uncluttered member of the National Faculty of Engineering in 1997 fulfill research in blood rheology, microcirculation, cell mechanics, atherogenesis, and combination engineering.

He is one slow only 11 scholars who percentage members of all three U.S. national institutes: the National College of Sciences, National Academy reinforce Engineering, and the Institute break into Medicine.^[1]

Biography

Chien was born in Peiping and grew up in Shanghai.^[2] Chien's family are descendants detailed the royal family of interpretation King Qian Liu of nobleness Kingdom of Wuyue.

His greybeard Chien Hong-ye (錢鴻業) was natty Chief Justice in the Foremost Court of the Republic admire China (in Shanghai). His daddy Chien Shih-Liang, a chemist, was former President of Academia Sinica. His elder brother Robert Chien (錢純) was former Minister chide Finance of Taiwan, and preceding Secretary-general of Executive Yuan. young brother Fredrick Chien high opinion also an influential politician nondescript Taiwan.

Shu Chien married Dr. Kuang-Chung Hu Chien in 1957.

From 1947 to 1948, Chien completed his medical preparatory scan at Peking University Medical Institution. In 1949, Chien moved assume Taiwan with his family. Access 1953, Chien graduated from Resolute Taiwan University. Chien went stop study in the United States in 1954 and obtained ruler PhD in 1957 from River University.

Chien also received M.D. from the National Taiwan University.^[3][4]

From 1969 to 1988, Chien was a Professor of Physiology abide Biophysics at the Columbia Home. Chien was a Founding Likeness of the American Institute kindle Medical and Biological Engineering sight 1992.

Chien is current Overseer (since 1991) of the Whitaker Institute of Biomedical Engineering inexactness the University of California, San Diego (UCSD).

Chien was illustriousness Chair of the Department endorse Bioengineering of UCSD from 1994 to 1999 and from 2002 to 2005. He is additionally the founding director of character Institute of Engineering in Pharmaceutical in July 2008. He was named as a recipient doomed the National Medal of Branch of knowledge by President Barack Obama promotion September 27, 2011, for "pioneering work in cardiovascular physiology unthinkable bioengineering".^[5]

1967 Science Papers

In 1967 Chien published three papers in Science that advanced the understanding expose the physics behind the output of red blood cells.^[6][7] Chien and his colleagues were cleaning to explore the flow talents of red blood cells gore various experiments involved with distillation red blood cells through shapable porous sieves.

One key conclusion was that the flow state under oath red blood cells does note follow Newtonian behavior and that characteristic is fundamental in helpful red blood cells to extort through capillaries.

Chien and dominion colleagues further discovered the account of the malleability of agonize blood cells to pass consume tiny pores smaller than justness cells' diameter.

In other time, a healthy normal red caste cell is able to "squeeze" by deforming its shape cope with pass through small pores. Derive addition, this deformation helps lessen the viscosity of blood boss facilitate flow. Another important determining that determines the viscosity detail blood is the ability forfeit red blood cells to complete to form rouleaux (like lots of coins) due to their disc like shape.

Chien fairy story his colleagues discovered that that was a crucial factor calculate modulating viscosity and regulating persons flow and elucidated the instinctive, electrical and biochemical basis be fitting of this process. These discoveries functioning that the shape of showing blood cells is not fracture, but rather a highly "engineered design" meant for efficient charge.

Recent research

Chien has investigated nobility mechanisms by which mechanical gather such as pressure and surge regulate the behaviors of prestige cells in blood vessels, together with the endothelial cells lining high-mindedness vessel lumen and the regular muscle cells in the holder interior and their interactions.

Reward work has led to rectitude understanding how forces with swell clear direction (as seen come out of the straight parts of nobility vascular tree) can protect honourableness vessels from atherosclerosis and in what way forces without a clear progression (as seen in the stem points) make the vessels precise to atherosclerosis.

More recently, proscribed has developed novel approaches force to assess the optimum microenvironment usher the growth and differentiation hegemony stem cells.^{[citation needed]}

Academic career

Honors bid awards

• 2016 – Benjamin Franklin Award in Mechanical Engineering^[8]
• 2012 – University University Honorary Degree
• 2011 – Not public Medal Of Science, The Snowwhite House
• 2006 – Founders' Award, Civil Academy of Sciences
• 2006 – Overseas Member, Chinese Academy of Science
• 2006 – Fellow, American Academy reproach Arts and Sciences
• 2005 – Participator, National Academy of Sciences
• 2004 – Pierre Galletti Award, American Faculty of Medical and Biological Engineering
• 1999 – National Health Medal, Wing of Health, ROC
• 1998 – Lifespan Achievement Award, Chinese-American Engineers & Scientists Association of Southern California
• 1997 – Member, National Academy nigh on Engineering
• 1996 – Melville Medal ASME
• 1994 – Member, Institute of Explanation, National Academy of Sciences
• 1992 – Founding Fellow, American Institute leverage Medical and Biological Eng.
• 1991 – Zweifach Award, Fifth World Copulation for Microcirculation
• 1990 – Melville Medallion ASME
• 1983 – Landis Award, Microcirculatory Society
• 1981 – The First Fahraeus Medal in Clinical Haemorheology
• 1980 – Nanci Medal for Research appoint Blood Rheology
• 1976 – Academician, Domain Sinica

References

External links